Wholesale Alpha-Cyclodextrin Powder α-CD CAS 10016-20-3
What is Alpha-Cyclodextrin?
Alpha-Cyclodextrin is a cyclic oligosaccharide composed of glucose units linked by α-1,4-glycosidic bonds; its molecular structure forms a hollow cylinder with a hydrophilic outer surface and a hydrophobic inner cavity. Functioning as a dietary fiber, this unique structure can have beneficial effects on blood cholesterol levels and the glycemic index. In food applications, it does not increase product viscosity, remains stable at high temperatures, and is suitable for use in low-pH environments. Due to its excellent solubility, Alpha-Cyclodextrin is particularly well-suited as an additive for beverages, such as dairy products and breakfast cereals.
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Comparison Item |
Alpha-Cyclodextrin (α-CD) |
beta -Cyclodextrin (beta -CD) |
|
Number of Glucose Units |
6 D-Glucose units |
7 D-Glucose units |
|
Molecular Formula |
C36H60O30 |
C42H70O35 |
|
Cavity Inner Diameter |
0.47~0.53 nm |
0.60~0.65 nm |
|
Cavity Depth |
0.79 nm |
0.79 nm |
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Water Solubility (25℃, g/100mL Water) |
Approx. 14.5 |
Approx. 1.85 (Low solubility at room temperature) |
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Crystalline Form |
White crystalline powder |
White crystalline powder |
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Suitable Guest Molecules for Inclusion |
Small molecules: C3~C4 alkanes, benzene, halogenated methanes, short-chain fatty acids |
Medium molecules: benzene derivatives, steroids, aromatic alcohols, most drugs, essential oils |
|
Polarity / Cavity Hydrophobicity |
Small cavity, weak hydrophobicity |
Moderate cavity, optimal hydrophobicity |
|
Dissolution Characteristics |
Easily soluble in cold water |
Requires hot water / ethanol for solubilization |
As a professional supplier of nutritional supplements, YTBIO is dedicated to providing you with high-purity, high-activity raw materials.
Direct raw material sourcing for consistent quality
We have established a comprehensive quality control system covering everything from raw materials to finished products. Our production process strictly adheres to GMP standards to ensure product safety and reliability.
Excellent compatibility and a wide range of applications
Our alpha-cyclodextrin features a hydrophilic exterior and a hydrophobic interior.
In-house manufacturing with over 12 years of experience
We operate our own factory, integrating raw material pretreatment, extraction, purification, drying, and packaging.
Robust production capacity and reliable delivery times
With an annual raw material processing capacity exceeding 500 tons and a monthly output of over 1,000 kg, we ensure a steady supply for everything from small sample requests to large-scale orders. We maintain ample inventory, allowing for rapid shipment of urgent orders within 3–5 days.
|
Item |
Specification |
|
Density |
1.624 |
|
Melting point |
278°C |
|
Boiling point |
1410.8 °C at 760 mmHg |
|
Refractive index |
1.591 |
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Flash point |
807.1 °C |
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Vapor pressure |
0mmHg at 25°C |
|
PSA |
474.90000 |
|
logP |
-13.05480 |
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Appearance |
White powder |
The Benefits of Alpha-Cyclodextrin
Regulating Gastrointestinal Function and Relieving Constipation
In the intestine, alpha-cyclodextrin is broken down by certain resident bacteria into a series of short-chain fatty acids, such as acetic acid, propionic acid, and butyric acid. These short-chain fatty acids inhibit the growth of harmful bacteria while promoting the proliferation of beneficial bacteria like *Bifidobacterium*. An increase in beneficial bacteria, in turn, boosts immunity and helps prevent conditions such as enteritis and constipation. Alpha-cyclodextrin is widely used in functional foods as a source of dietary fiber or as an ingredient to help manage metabolic syndrome.

Preventing and Managing Diabetes
In the intestine, alpha-cyclodextrin is broken down by certain resident bacteria into a series of short-chain fatty acids, such as acetic acid, propionic acid, and butyric acid. These short-chain fatty acids inhibit the growth of harmful bacteria while promoting the proliferation of beneficial bacteria like *Bifidobacterium*. An increase in beneficial bacteria, in turn, boosts immunity and helps prevent conditions such as enteritis, colon cancer, dysentery, and constipation. Alpha-cyclodextrin is widely used in functional foods as a source of dietary fiber or as an ingredient to help manage metabolic syndrome.
Weight Loss
Alpha-cyclodextrin can encapsulate excess fat (particularly animal fat) and facilitate its excretion from the body; it also inhibits sugar absorption, thereby aiding in weight loss and body weight management.
Enhancing Additive Stability
When used in combination with additives such as Vitamin E, natural pigments (e.g., beta-carotene, chlorophyll), and food flavorings (e.g., rose oil, anethole), alpha-cyclodextrin enhances their stability, facilitating long-term storage and maintaining their integrity within food products. It also finds extensive application in the household and personal care industry.

In cosmetics manufacturing, cyclodextrins serve as emulsifiers and quality enhancers. They stabilize raw materials within cosmetic formulations, enhance the stability of active ingredients and volatile components, improve emulsion stability, and increase the solubility of lipophilic substances. Additionally, alpha-cyclodextrin offers deodorizing properties (such as eliminating bad breath) and preservative effects, making it suitable for use in the production of toothpaste and tooth powder.
Alpha-Cyclodextrin Production Process
The preparation of alpha-cyclodextrin typically relies on the differing water solubilities of various cyclodextrin types; separation and purification are achieved through fractional concentration of the reaction mixture. Production generally employs high substrate concentrations and short reaction times to maximize the proportion of alpha-cyclodextrin in the product. Consequently, the reaction mixture contains significant amounts of unreacted starch and dextrin. Large-molecule starch and dextrin are first removed—typically via filtration—to isolate the crude cyclodextrin product, which is then refined through activated carbon decolorization and ion-exchange desalting. The refined filtrate is concentrated to first crystallize and separate out beta-cyclodextrin; subsequently, amylase is added to saccharify the remaining filtrate. Finally, the solution undergoes further concentration and low-temperature standing to yield the alpha-cyclodextrin product.

FAQ
Q1: What is the least arrange amount for the product?
A1: Our least arrange amount is ordinarily 1kg for test orders. For commercial orders, we prescribe 25kg to optimize shipping costs and guarantee superior pricing.
Q2: How ought to I store the powder to keep up its quality?
A2: Store in a cool, dry, and ventilated put absent from coordinate daylight. Keep holders firmly fixed to anticipate dampness assimilation. Legitimate capacity guarantees 24 months rack life.
Q3: What testing strategies do you utilize for quality control?
A3: We utilize Tall Execution Fluid Chromatography (HPLC) and UV spectroscopy strategies to guarantee immaculateness and consistency. Each bunch incorporates comprehensive microbiological testing.
Q4: Can you give specialized back for definition development?
A4: Completely. Our specialized group offers definition direction, application suggestions, and compatibility testing bolster to offer assistance optimize your products.
Q5: What are the commonplace lead times for orders?
A5: Test orders transport inside 3-5 commerce days. Commercial orders regularly require 7-15 days depending on amount and bundling necessities.
Why Choose YTBIO's Alpha-Cyclodextrin?

Email: sales@sxytbio.com
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